Updates

June 24, 2019June 24, 2019
New Genentech Study to Investigate Familial Alzheimer’s Progression and Response to Crenezumab

Genentech, a subsidiary of Roche, has launched a new substudy to learn more about the progression of early-onset familial Alzheimer’s disease, as part of its ... Read more
June 21, 2019June 19, 2019
The ‘Longest Day’ Sheds Light on Alzheimer’s Disease

The Alzheimer’s Association has chosen the summer solstice, June 21, to shed light on Alzheimer’s disease and to raise awareness about the mind-altering, life-changing ... Read more
June 21, 2019June 21, 2019
1st U.S. Patient Enrolled in Phase 2a Trial Evaluating Vafidemstat for Alzheimer’s

A Phase 2a trial testing Oryzon’s investigational therapy vafidemstat for Alzheimer’s disease has enrolled its first patient in the U.S. The trial (NCT03867253), called ... Read more
June 19, 2019June 19, 2019
Vaccine Reduces Tau Tangle Formation, Improves Cognitive Functioning in Alzheimer’s Mouse Model

A vaccine produced using virus-like particles was able to improve cognitive functioning and reduce the accumulation of tau protein aggregates — a hallmark of ... Read more
June 17, 2019June 17, 2019
Presence of Mouth Bacteria Linked to Risk of Alzheimer’s, Study Shows

A connection discovered between Alzheimer’s and the bacteria that cause gum disease suggests that improved oral hygiene may decrease the risk of developing the ... Read more

Columns, Treading Dark Waters - a Column by Ray Burow

Caring for the Opposite Sex: Dealing with Intimacy Challenges
June 14, 2019June 12, 2019
In the United States, 2.1 million men age 65 and older have Alzheimer’s disease. ...
News

AxoSim Licenses Mini-Brain Technology to Pursue Therapies for Alzheimer’s, Other Disorders
June 14, 2019June 14, 2019
AxoSim has acquired exclusive rights to lab-grown brain miniatures, coined “Mini-Brain,” a technology developed at Johns ...
News

Host of Activities Planned for Alzheimer’s and Brain Awareness Month
June 12, 2019June 12, 2019
Scores of efforts to mark June’s Alzheimer’s & Brain Awareness Month are designed to ...
Columns, Dementia Days - a Column by Niko Mann

My Guilt Was Endless as My Mom’s Disease Progressed
June 11, 2019June 7, 2019
Mourning a person who is still living is a sad and surreal experience. I’ve ...
News

High Levels of ‘Bad’ Cholesterol Linked to Increased Risk of Early-onset Alzheimer’s, Study Suggests
June 10, 2019
High levels of “bad” cholesterol, known as low-density lipoprotein (LDL), might increase the risk ...
Columns, Treading Dark Waters - a Column by Ray Burow

Mourning Is a Natural Process for Caregivers
June 7, 2019June 5, 2019
We tend to categorize loss. The loss of a child is the pinnacle of ...

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ProMIS’ PMN310 Antibody Candidate Shows Greater Effect, Less Risk Than Other Therapies, According to Data
June 7, 2019June 7, 2019
ProMIS Neurosciences’ candidate PMN310 can specifically target toxic clusters of soluble amyloid-beta protein, and ...
Alzheimer’s Diagnostics Accelerator Program Awards Nearly $3.5M to Develop Early-detection Methods
June 5, 2019June 5, 2019
Selected through the Alzheimer’s Drug Discovery Foundation’s (ADDF) Diagnostics Accelerator program, four scientists will ...
Virtual Reality May Improve Quality of Life of Hospitalized Dementia Patients, Study Says
June 3, 2019June 3, 2019
Tips to Help Members of the Sandwich Generation Balance Responsibilities
May 31, 2019May 29, 2019
Antibodies That Target Neurotoxic Proteins in Alzheimer’s Are Identified
May 31, 2019May 31, 2019
Early Brain Alterations May Occur Decades Before Onset of First Symptoms, Researchers Say
May 29, 2019May 29, 2019

The Death of Denial
May 28, 2019May 23, 2019
I was helping Mom in the bathroom when suddenly she slumped over, unable to hold ...
More than a Million Children Provide Familial Care in the US
May 24, 2019May 23, 2019
ADDF Grants $1.5M to Fund U.S. Arm of Phase 2a Trial for Vafidemstat in Alzheimer’s Patients
May 24, 2019May 24, 2019
PRI-002, Oral Therapy Candidate for Alzheimer’s, Deemed Safe in Phase 1 Trial
May 22, 2019May 22, 2019

Investigational Alzheimer’s Therapy NNI-362 Receives FDA Approval to Enter Phase 1 Clinical Studies
May 20, 2019May 20, 2019
The U.S. Food and Drug Administration has approved Neuronascent’s investigational new drug (IND) application ...
Caregivers Can Help Preserve Alzheimer’s Patients’ Dignity
May 17, 2019May 16, 2019
2 Planned Clinical Trials to Test Ways of Preventing Alzheimer’s at Early Stages
May 17, 2019May 17, 2019

News

Sleep Molecules May Represent a New Blood Biomarker for Earlier Diagnosis, Study Suggests
May 15, 2019May 15, 2019
High blood levels of primary fatty acid amides (PFAMS), a class of fatty molecules ...
News

UNC Launches Training Program to Improve Dementia Patients’ Care
May 12, 2019May 13, 2019
A new program called the Dementia Friendly Hospital Initiative is set to be launched ...
Columns, Treading Dark Waters - a Column by Ray Burow

Despite Alzheimer’s, My Mom Never Lost Sight of Motherhood
May 10, 2019May 8, 2019
I recently discovered this article celebrating Mother’s Day and found it to be an ...
News

Family Caregivers of Dementia Patients May Benefit from Learning Positive Emotion Skills, Study Suggests
May 10, 2019May 10, 2019
An online program that teaches how to focus on positive emotions can help caregivers ...
News

Tetra Launches Phase 2 Trial Testing Treatment to Improve Working Memory in Older Patients
May 8, 2019May 8, 2019
Tetra Discovery Partners is launching a Phase 2 clinical trial for BPN14770 — found ...
News

#AANAM – Memantine as Add-on Therapy Seen to Ease Psychosis, Other Advanced Alzheimer’s Symptoms
May 6, 2019May 6, 2019
Adding memantine to a cholinesterase inhibitor can significantly ease certain neuropsychiatric symptoms, including psychosis ...
Columns, Treading Dark Waters - a Column by Ray Burow

Caregivers Face Isolation, but You Can Find Ways to Connect
May 3, 2019May 2, 2019
Caregivers are often isolated. This may be particularly true of those who provide care ...
News

PALS Uplifts the Spirits of Rare-Disease Patients by Offering Free Flights
May 1, 2019
Cumbersome security procedures, rising airfares, and shrinking legroom have made commercial air travel difficult ...
News

Long-term Treatment with Thiazide Diuretics May Lower Risk of Bone, Hip Fractures, Study Suggests
May 1, 2019May 1, 2019
Long-term use of thiazide diuretics — a hypertension medication — may lower the risk ...
Columns, Dementia Days - a Column by Niko Mann

Panic at the Disco
April 30, 2019April 26, 2019
Caring for a loved one as they battle dual terminal illnesses can be overwhelming, ...
News

Simple Blood Test May Become Useful Biomarker of Alzheimer’s Progression and Treatment Response, Study Suggests
April 29, 2019April 29, 2019
Blood levels of a nerve cell-derived component, known as neurofilament light chain, could be ...
Columns, Treading Dark Waters - a Column by Ray Burow

Good Health Is Crucial to Caregiving
April 26, 2019April 24, 2019
A recent study conducted by Johns Hopkins University indicates that caregivers aren’t nearly as ...
News

Researchers Create Human-like Antibody for Treatment of Alzheimer’s, PSP
April 26, 2019April 26, 2019
Tau bio-logic and LifeArc researchers have generated a human-like antibody called TBL-100 for the treatment ...
News

New Model of Blood-Brain Barrier May Aid in Predicting Therapies Able to Best Treat Patients, Scientists Say
April 24, 2019April 24, 2019
A cellular model that simulates the blood-brain barrier — a membrane that protects against viruses ...
Columns, Dementia Days - a Column by Niko Mann

When to Take the Driver’s Seat with Dementia Caregiving
April 23, 2019April 22, 2019
Caring for someone with dementia as they lose independence is challenging, especially when the ...
News

Cognitive Training Improves Reasoning and Memory in Adults with Mild Impairment, Pilot Study Finds
April 22, 2019April 22, 2019
Cognitive training alone — without the use of direct brain stimulation — may significantly ...
News

Anti-Inflammatory Naproxen Fails to Prevent Alzheimer’s Progression, Phase 2 Trial Confirms
April 17, 2019April 17, 2019
Treatment with naproxen, an anti-inflammatory medication, failed to prevent the progression of Alzheimer’s in ...
Columns, Dementia Days - a Column by Niko Mann

After Her Big Decision, Mom Just Lets the Good Times Roll
April 16, 2019April 12, 2019
When my mom was diagnosed with terminal uterine cancer, she was displeased to say ...

November 8, 2017November 8, 2017

Anavex ‘Cautiously Optimistic’ After Noting Cognitive Improvement in Alzheimer’s Treatment

News

Anavex Life Sciences says its Alzheimer’s drug candidate Anavex 2-73 may have a role in treating the disease. Data from a long-term extension trial, although small, indicated that the therapy improved cognitive and functional measures in patients. According to data ... Read more

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